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P†ó+©ª  -¾  qGACNNNNNNGTC,CCAGGCCTGG,GATCCGGATC,CCWGGTACCWGG,CCANNNNNTGG,CCAGGNNNTGG,CCANNNCCTGG,CCAGGNCCTGG,GCACNNNAACGTTNNNGTGC,CACNNNGTG,CCNNNNNNNGG,AACNAACRYGTGCGTGC,GCACGCACRYGTTNGTT,GCACNAACRYGTTNGTGC,AACGCACRYGTGCGTT,GACNNNNNGTC,GAANNNNNNNTTGG,CCAANNNNNNNTTC,CACNNNNGTG,AACACNNNNGTGC,GCACNNNNGTGTT,GCANNNNNNTGC,GAACNNNNNNTCC,GGANNNNNNGTTC,CAGNNNCTG,CCAGGNNCTG,CAGNNCCTGG,CCWGGGCCC,GGGCCCWGG,CCWGGGCCCWGG,AACNNNNNNGTGCACNNNNNNGTT,GACNNNGTC,GAANNNNTTC,CCWGGTACC,GGTACCWGG,CCWGGWCCWGG,ACNNNNGTAYC,GRTACNNNNGT,CCWGGYRCCWGG,GAAGNNNNNNTAC,GTANNNNNNCTTC,AACGGCNNNGTGC,GCACNNNGCCGTT,GCACGGCNNNGTT,AACNNNGCCGTGC,CGANNNNNNTGC,GCANNNNNNTCG,CGATCNNNNTGC,GCANNNNGATCG,TGANNNNNNTCA,TGATCNNNNTCA,TGANNNNGATCA,TGATCNNGATCA,AACCTGCNNGTGC,GCACNNGCAGGTT,GCACCTGCNNGTT,AACNNGCAGGTGC,GCCNNNNNGGC,AACNNNNNNGTGCMC,GKGCACNNNNNNGTT,CCWGGNCCWGG,AACTGGGNNGTGC,GCACNNCCCAGTT,GCACTGGGNNGTT,AACNNCCCAGTGC,GACNNNNGTC,GAGNNNNNCTC,CCWGGTCTC,GAGACCWGG,GATNNNNATC,GATCNNNATC,GATNNNGATC,GATCNNGATC,CCWGGCGCCWGG,ACNNNNNCTCC,GGAGNNNNNGT,AACNNNNNNGTGCAG,CTGCACNNNNNNGTT,GATCATGATC,CCWGGNNCCWGG,AACTGGNNNGTGC,GCACNNNCCAGTT,GCACTGGNNNGTT,AACNNNCCAGTGC,AACNAACCGGTGCGTGC,GCACGCACCGGTTNGTT,GCACNAACCGGTTNGTGC,AACGCACCGGTGCGTT,GCANNNNNTGC,GCACNNNNNNGTTCGAACNNNNNNGTGC,CCTNNNNNAGG,GCNNNNNNNGC,CCANNNNNNTGG,CCAGGNNCCTGG,CCTGGCCAGG,CAANNNNNGTGG,CCACNNNNNTTG,TTTAAACNNNNNNGTGC,GCACNNNNNNGTTTAAA,GCACNNNNNNGTTTAAACNNNNNNGTGC,CCAGGNCCY,RGGNCCTGG,CCWGGGNCCTGG,CCAGGNCCCWGG,AAGNNNNNCTT,GAYNNNNNVTC,GABNNNNNRTC,GAYNNNNNRTC,GATCNNNNVTC,GABNNNNGATC,GAYNNNNGATC,GATCNNNNRTC,GATCNNNGATC,GTYAACNNNNNNGTGC,GCACNNNNNNGTTRAC,GCACNNNNNNGTTAACNNNNNNGTGC,GATCNGATC,TAACTATAACGGTCCTAAGGTAGCGA,TCGCTACCTTAGGACCGTTATAGTTA,CTCTCTTAAGGTAGC,GCTACCTTAAGAGAG,TAGGGATAACAGGGTAAT,ATTACCCTGTTATCCCTA,GTTAACNNNNNNGTGC,GCACNNNNNNGTTAAC,AACNAACGCGTGCGTGC,GCACGCACGCGTTNGTT,GCACNAACGCGTTNGTGC,AACGCACGCGTGCGTT,TCCAACNNNNNNGTGC,GCACNNNNNNGTTGGA,CAYNNNNRTG,AACAYNNNNGTGC,GCACNNNNRTGTT,GTTTAAACNNNNNNGTGC,GCACNNNNNNGTTTAAAC,CCWGGCGCC,GGCGCCWGG,CCWGGNNCC,GGNNCCWGG,GATCGCGATC,AACNAACATGTGCGTGC,GCACGCACATGTTNGTT,GCACNAACATGTTNGTGC,AACGCACATGTGCGTT,TGGCAAACAGCTATTATGGGTATTATGGGT,ACCCATAATACCCATAATAGCTGTTTGCCA,ATCTATGTCGGGTGCGGAGAAAGAGGTAATGAAATGG,CCATTTCATTACCTCTTTCTCCGCACCCGACATAGAT,AACNNGCACGTGCNNGTT,GAACNNNNNCTC,GAGNNNNNGTTC,CCAGGWCCY,RGGWCCTGG,CCWGGGWCCTGG,CCAGGWCCCWGG,CCAGGWCCTGG,TTATAACNNNNNNGTGC,GCACNNNNNNGTTATAA,GCACNNNNNNGTTATAACNNNNNNGTGC,GAACNNNNNNTAC,GTANNNNNNGTTC,GGCCNNNNNGGCC,AACNNACTAGTGC,GCACTAGTNNGTT,AACTAGTNNGTGC,GCACNNACTAGTT,AACNAACTAGTGCGTGC,GCACGCACTAGTTNGTT,GCACNAACTAGTTNGTGC,AACGCACTAGTGCGTT,AACNNNAACGTGCNNGTGC,GCACNNGCACGTTNNNGTT,GCACCCANNNGTT,AACNNNTGGGTGC,TTAACNNNNNNGTGC,GCACNNNNNNGTTAA,CACNNNNNNTCC,GGANNNNNNGTG,CACNNNNGATCC,GGATCNNNNGTG,GATCTAGATC,CCANNNNNNNNNTGG,CCAGGCCT,AGGCCTGG,CCTCGAGG,GATCCGGA,TCCGGATC,GGCGCGCC,GCGATCGC,CCWGGWCC,GGWCCWGG,GATCGATC,GATCATGA,TCATGATC,GCGGCCGC,CCTGGCCR,YGGCCAGG,CCWGGNCC,GGNCCWGG,GGCCGGCC,RTGCGCAY,GATCNNGA,TCNNGATC,CGCGCGCG,CCTGGCCA,TGGCCAGG,CGCCGGCG,GTTTAAAC,GATCGCGA,TCGCGATC,TTAATTAA,VCTCGAGB,CCTGCAGG,CRCCGGYG,CGTCGACG,ATTTAAAT,GCCCGGGC,GATCTAGA,TCTAGATC,CACCTGC,GCAGGTG,CCTNAGG,GATCGAT,ATCGATC,CCTCAGC,GCTGAGG,GCTNAGC,CCTNAGC,GCTNAGG,GCTCTTC,GAAGAGC,GGTNACC,CGGWCCG,ACCWGGT,RGGNCCY,CCTGGAG,CTCCAGG,GGTGATC,GATCACC,GATCNGA,TCNGATC,GGGWCCC,GAAGATC,GATCTTC,CCCWGGG,TCCNGGA,TCCWGGA,RGGWCCY,TTATAA,AGGCCT,GACGTC,GTMKAC,TCCGGA,TGCGCA,ACCTGC,GCAGGT,GGTACC,AGTACT,GGYRCC,CCGCTC,GAGCGG,AACGTT,YGGCCR,RAATTY,CTGAAG,CTTCAG,CACGTG,GRCGYC,AGCGCT,CTTAAG,ACRYGT,ACCGGT,ACTAGT,CACGTC,GACGTG,GWGCWC,GTGCAC,CYCGRG,GGGCCC,ATTAAT,CCTAGG,TTCGAA,GCTAGC,GKGCMC,TGGCCA,GGATCC,GRGCYC,ATCGAT,CACGAG,CTCGTG,GGCGCC,GAAGAC,GTCTTC,GCATGC,GTATCC,GGATAC,TGATCA,ACTGGG,CCCAGT,CTRYAG,RGCGCY,AGATCT,GGNNCC,CTGGAG,CTCCAG,CTTGAG,CTCAAG,CGATCG,GGTCTC,GAGACC,YACGTR,CCNNGG,GAATGC,GCATTC,WCCGGW,GCAATG,CATTGC,RCCGGY,GCGCGC,GAGGAG,CTCCTC,CGGCCG,CCCAGC,GCTGGG,GTGCAG,CTGCAC,CGRYCG,CGTACG,CGTCTC,GAGACG,CCATGG,TCGCGA,GDGCHC,TGTACA,TCATGA,ACATGT,GTATAC,CCWWGG,CTCTTC,GAAGAG,GCNNGC,CCRYGG,GTTAAC,RCATGY,TACGTA,RGATCY,GCGATG,CATCGC,GCAGTG,CACTGC,CCCGGG,CCGCGG,TTTAAA,GGCGGA,TCCGCC,GAGCTC,GATATC,CTGRAG,CTYCAG,CAGCAG,CTGCTG,GAATTC,ATGCAT,CATATG,GTYRAC,AAGCTT,GTNNAC,TCNNGA,CAATTG,ACGCGT,TCCRAC,GTYGGA,GCCGGC,CMGCKG,GCCGAG,CTCGGC,CTCGAG,CTGCAG,CAGCTG,GTCGAC,CTYRAG,AATATT,GATCGA,TCGATC,GACCGA,CACCCA,TCGGTC,TGGGTG,WGTACW,TARCCA,TGGYTA,TCTAGA,GGATC,GATCC,CCWGG,GTCTC,GAGAC,GCWGC,GGNCC,CCSGG,GGTGA,TCACC,GGWCC,GCAGC,GCTGC,CCATC,GATGG,ACGGC,GCCGT,GCNGC,CCNGG,GCATC,GATGC,ACTGG,CCAGT,GGATG,CATCC,CTCAG,CTGAG,GGGAC,GTCCC,ACNGT,CTNAG,CAGTG,CACTG,GACGC,GCGTC,CCCGC,GCGGG,GANTC,CGWCG,TCNGA,CCTTC,GAAGG,GTNAC,GAAGA,TCTTC,GAGTC,GACTC,GTSAC,GAWTC,GCSGC,CASTG,ATGAA,TTCAT,ACGGA,TCCGT,CGCG,CCGC,GCGG,GTAC,AGCT,GCGC,CTAG,GATC,GGCC,CCGG,CATG,RGCY,YATR,ACGT,TGCA,AATT,CCTC,GAGG,TTAA,ASST,TCGA                                                                                                                                                                                                                                                 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                        !   &      %   (      #            w   H         -         &   M                                                                                                                                                                     )                                                                                                                                                                                                                                                                                                        
                                             	                                                                                                                   !         	   ;  	                             	 
        ! &  % (  #    w H   -   & M   sç  tÙ  tó  u3  yM  ~  „g)ƒþU ¸ ¹ gèe"ÈÚˆç*3W rÊ/QJžž
ñûh
—Üû×	L<<}yÁ/ÇL3(PW»ns†ÖÙÜ"zÀê)+UpŽû»-pÄðSyÂpâ;LNÜ2t¼W rúËW Â(rúW rúp	×
vÊÑë	06yð T ¢ºæŽû8æûœ°‹4K4Òiü¸› “´2µ3qÿ;ƒ”2Ê	† d) Y öB ´2ü4~G¥jB¾# –«”
Q («×¦ï&n+	4% 
‘<dŠ~î
�!£¨U·Âžõèy€bÈ	kàŠ,Q Z
&f®ïü n ô Çà H×	,
µ�O»Ð×	µ,�ó±› “ÇšÕùJ› “Ï‘×	µÙ<ý› “Hµ�O‹Ú	B‘ÄQ &d
â'	¯$–EtÖiËa!�'æhïQ aiûm&Ï:‚? Q › œ Æ “Ôý´(«[¶Â×þLH¦ªÑï£&23z4q|
j…Ä&þîÿ^ (/pþ   Y Z   ö÷ECíJ Oô‹â‹È£Ô-²«Ù°s¾OŽ!†<B—"ª&UtXp7L7:dŠ!£¿Ì¼Ÿ 1,dŠþîn
žFÿ!£ö íûè› “ÏH‘µ×	,
µ�ÙO»Ð/	ï íJâ‹ÈÔÓà]	iü—¸Ø &U ·såvtÎÒæ^l—‹»à6£ÀX‚â¾fp-í«ïÃâ… ýÏ:±ð	
cn‚ùi~ž1ê
Í
Ä!±Òaoé
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j…®Ä�ó±ÎP	:ŒàG©	…lm
Ô	À!”
çÕÙ
�0P:Aœx˜… ýIð	1c¹“—~þ²
oújŸ Z ÷EC¡O\Õõ‹N3s£_ ÷ $)0q3	^d”ö 1 L y #H`yÖÙÜâ†Ç/¼JÒ
@ˆVYš=O Øí"%m› œ “”µåéúI3=¶C ‚ ¡ g^
½uô·	%� ç¨	™
¯µé3 L y #`yâÇ/¼J@š=O Øí"%m1 HÖÙÜ†Ò
ˆVY\Â	„3c÷´
ÓO¾ìF‰oÕv€
 . 1 L O y � Õ ð #EH`cyŒÖÙÜßâ†Ç/¼&4JŽ	s
Ò
í
@ˆVYš)Ä:=O >‡ #Øí"%m¢¥ª­ C Z ‚ ¡ g÷EC¡^
½uO\Õõ‹N3s£V�ANª
ÈLfÄ	|˜—¯ð$|–Tí	¤ÏEÛ¸�t×œ
P]³
Ò‡WBÃÂ…L·‚
ÿ>"žDÝ†5) ´íN2wF2”&^©ý½
ÀùÏÝ±ÿ\†n.º L¡Ó>·"‚
žDÝ†ÿŸ5_ÇÎ
Q^XÅ"²/–Òao{é
D­B5©Ê+ § Z
Yø| nHŠËð¡±Æçm‡v}7ÀØä.z¢h0Fx}	T•ê`@{ IÅ¦ Éo‡ùm§‚�jq‹X„a=¸!Åƒ
û
ÄKÑ2€ … `Œ–.õ‚™	ý‰¬ÉÃ kYôÔ
´cBQ~ ã  ©<“§COã	Ÿ
8r½ØL‹²èñ"q+d
à]	Ê	
i™ü—FKN¸j ˆ ’}fþ+Ôh0xT¢F}ê`~ ã  “OŸ
rè"ä.z	•@{ IÅ. O � Õ ð EcŒß&4Ž	s
í
)Ä:>‡ #¢¥ª­–Ò_aÇo{Î
é
D­BQ^XÅ5©"²Ê/Z‰b¶ãï—¸ËÖê ±
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4~Ã‰‹Yqé¬Ž ´ ñ /¢®�²¾ÇÓÝèèSn+	t
Ÿ/4;~ˆ?$¦«. O Î Õ Ecqv}‰¦ß"&47üŽ	û	H
í
Ú5¨�)¨ÄfÀ'‡ªØ ¢­ ¬"S•
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—ô}ê˜ü?MnŠËXZ'prëDý ƒW­Öx©Kg¶]Ÿõ§±9Þ˜† þÿ<JÐ;²ïÍ	ñ	
2D™\doº ƒúæ”£)˜jŽŸœ =e”‹Hå•ï
úJÆØã‘Q"=¤·©C ƒ ¢ Ý g¿˜^
P¾#·u�"«åžî0	¹
Ý
+5 ðJ®Äã%Â 0 œ ï 7=Ge”ºÔH{‹äPjŸÉÖøAIQju1¥«ñ%<HÑåš¨¶•©ï
T^¸ú!JVÁÞ	U¤½ÂðJ¬ÆØã,?‘¢âøAx~…_‰‘™²½Pe¯7Qf|é"¿:o‚Ÿ1¤Ê=š¤·ã‹©¯¤S“åý5žîb$	0	c	@
w
¹
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×
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+5a„ÔÖØ 6óg°ðDJ”®Äã%h!#(©«A[]cæ™¬®ºðÂÍÕ×Qeg�’GVo á õ ÈQŽ‘ÿ*6
’2 %¶½@.r»Ø	Ì
$å?Ž¶Ÿ�–©áEÇ !TÅÓC2‚üVùY¸ÃÝÇ
ÆøÔ0^:ŸáöKXq/!(BktŽ ³òøü3NÂédqz�¼Ùî6‹l¶ÛYª:~�e´þ¼#œòzœ7:Fã	×E`L}‚­ù7:D7AÈ/´´²ßg±.=Ÿ°»ÇÒ4
¡È³èöû/›Ö`ˆU¯ÔýI#4@•ÖúJWo Å á õ Èí{·äì1®ÉIu1«%QŽÑ‘¨Úÿ*6©â
T’¸¥2ÁÖ9ÂÑäðJ},¢®âAx~…÷_‘½P7|é2¿o�Ÿ
1Ò"S %ñ:¦Ýé	�bWqƒŒž�îô²   -<AlignableSequences trimStringency="Medium"/>  !<AdditionalSequenceProperties><UpstreamStickiness>0</UpstreamStickiness><DownstreamStickiness>0</DownstreamStickiness><UpstreamModification>FivePrimePhosphorylated</UpstreamModification><DownstreamModification>FivePrimePhosphorylated</DownstreamModification></AdditionalSequenceProperties>
  %Z<?xml version="1.0"?><Features nextValidID="22"><Feature recentID="0" name="shRNA1" type="misc_feature" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1"><Segment range="6576-6626" color="#a6acb3" type="standard"/></Feature><Feature recentID="1" name="AmpR" directionality="1" translationMW="31558.16" type="CDS" allowSegmentOverlaps="0" cleavageArrows="2473" consecutiveTranslationNumbering="1" hitsStopCodon="1" detectionMode="exactProteinMatch"><Segment name="signal sequence" range="2405-2473" color="#ccffcc" type="standard" translated="1"/><Segment range="2474-3265" color="#ccffcc" type="standard" translated="1"/><Q name="codon_start"><V int="1"/></Q><Q name="gene"><V text="&lt;html&gt;&lt;body&gt;&lt;i&gt;bla&lt;/i&gt;&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="note"><V text="&lt;html&gt;&lt;body&gt;confers resistance to ampicillin, carbenicillin, and related antibiotics&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="product"><V text="&lt;html&gt;&lt;body&gt;Î²-lactamase&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="transl_table"><V int="1"/></Q><Q name="translation"><V text="MSIQHFRVALIPFFAAFCLPVFA,HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRIDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW*"/></Q></Feature><Feature recentID="2" name="pUC ori" directionality="1" type="rep_origin" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1"><Segment range="3436-4024" color="#ffff00" type="standard"/><Q name="direction"><V text="RIGHT"/></Q><Q name="note"><V text="&lt;html&gt;&lt;body&gt;high-copy-number ColE1/pMB1/pBR322/pUC origin of replication&lt;/body&gt;&lt;/html&gt;"/></Q></Feature><Feature recentID="3" name="hPGK promoter" directionality="1" type="promoter" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1"><Segment range="6840-507" color="#ffffff" type="standard"/><Q name="note"><V text="&lt;html&gt;&lt;body&gt;human phosphoglycerate kinase 1 promoter&lt;/body&gt;&lt;/html&gt;"/></Q></Feature><Feature recentID="4" name="f1 ori" directionality="1" type="rep_origin" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1"><Segment range="1819-2274" color="#ffff00" type="standard"/><Q name="direction"><V text="RIGHT"/></Q><Q name="note"><V text="&lt;html&gt;&lt;body&gt;f1 bacteriophage origin of replication; 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  £<Notes>
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<Type>Synthetic</Type>
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<CustomMapLabel>pLV3-U6-Control-shRNA-Blast</CustomMapLabel>
<UseCustomMapLabel>1</UseCustomMapLabel>
<Created UTC="16:0:0">2016.9.4</Created>
<LastModified UTC="21:0:4">2025.7.8</LastModified>
<SequenceClass>UNA</SequenceClass>
<TransformedInto>unspecified</TransformedInto>
</Notes>
  Y      K         
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   )<?xml version="1.0"?><CustomEnzymeSets/>
